In search of the optimal macrocyclization site for neurotensin. Sousbie M, Besserer-Offroy É, Longpré JM, Leduc R, Sarret P, Marsault É. ACS Med Chem Lett. 2018 Jan 29. doi: 10.1021/acsmedchemlett.7b00500

Use of Molecular Modeling to Design Selective-NTS2 Neurotensin Analogues. Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F. J Med Chem. 2017 Apr 3. doi: 10.1021/acs.jmedchem.6b01848

Signaling signature of neurotensin receptor type 1 with endogenous ligands. Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Eur J Pharmacol. 2017 Mar 21. doi: 10.1016/j.ejphar.2017.03.046

Structure-activity relationship of novel macrocyclic biased apelin receptor agonists. Murza A, Sainsily X, Côté J, Bruneau-Cossette L, Besserer-Offroy É, Longpré JM, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É. Org Biomol Chem. 2016 Dec 7. PMID: 27924341

Design, Synthesis, and Biological Evaluation of Novel CXCR4 Inverse Agonists Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault E, Escher E Org Biomol Chem. 2016 Oct 04. DOI: 10.1039/C6OB01484D

Structure Activity Relationship and Signaling of New Chimeric CXCR4 Agonists. Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault E, Escher E. J Med Chem. 2016 Jul 19. PMID: 27434274

Identification of 2-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic acid (NTRC-844) as a selec-tive antagonist for the Rat Neurotensin recep-tor type 2. Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpre JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. ACS Chem Neurosci. 2016 Jun 30. PMID: 27359371

Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpre JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault E. J Med Chem. 2016 Mar 17. PMID: […]

Stereoselective synthesis of β-(5-arylthiazolyl) α-amino acids and use in neurotensin analogues. Hapău D, Rémond E, Fanelli R, Vivancos M, René A, Côté J, Besserer-Offroy É, Longpré JM, Martinez J, Zaharia V, Sarret P, Cavelier F. Eur J Org Chem. 2016 Jan 18. DOI: 10.1002/ejoc.201501495  

Synthesis, in vitro and in vivo characterization of (L)-(trimethylsilyl)alanine containing neurotensin analogues. *Fanelli R, *Besserer-Offroy É, René A, Côté J, Tétrault P, Collerette-Tremblay J, Longpré JM, Leduc R, Martinez J, Sarret P, Cavelier F. J Med Chem. 2015 Sep 8. PMID: 26348111